Kết quả hồi sức sau ghép gan ở trẻ teo mật bẩm sinh tại Bệnh viện Nhi Trung ương

Abstract

Biliary atresia is the leading cause of end-stage liver disease in children, and liver transplantation remains the only definitive treatment capable of restoring hepatic function and improving long-term survival. The postoperative intensive care period plays a critical role in maintaining graft function, preventing complications, and stabilizing the overall clinical condition. This study included 39 pediatric patients who underwent liver transplantation at Vietnam National Children’s Hospital from January 2019 to June 2024; the purpose of the study was to evaluate outcomes during the intensive care phase. The mean duration of mechanical ventilation was 24.7 ± 17.1 hours. Postoperative hemorrhage occurred in 35.9% of patients, while 35.9% experienced no surgical complication. Pleural effusion was present in over 50% of cases; intra-abdominal infection and chylous leakage occurred in 17.9% and 12.8%, respectively. Liver enzymes and bilirubin increased in the first 1 - 2 postoperative days but progressively declined to near-normal levels before discharge. Hematologic parameters, coagulation profiles, albumin, and renal function also stabilized. Strengthening complication surveillance, standardizing intensive care management, and enhancing multidisciplinary coordination are essential to ensure early detection, timely intervention, optimized graft function, and improved long-term prognosis.