Hem-o-lok clip migration causing secondary common bile duct (CBD) stone after laparoscopic common bile duct exploration: A case report and literature review

Le Quang Hung, Nguyen Trung Duc, Le Tuan Anh, Ha Luong Duy Khanh, Phan Quoc Hung, Nguyen Van Viet

Main Article Content

Abstract

Hem-o-lok clip migration into the common bile duct (CBD) and subsequent stone formation is a rare, late complication following laparoscopic common bile duct exploration (LCBDE). The clinical presentation often mimics that of primary CBD stones, including biliary colic and cholangitis. We report the case of a 79-year-old female patient diagnosed with a secondary CBD stone formed around a migrated surgical clip just four months after LCBDE. The patient was admitted with progressively increasing right upper quadrant (RUQ) pain. Imaging (MRI) confirmed biliary duct dilation and an impacted stone in the distal CBD. The patient was successfully treated with Endoscopic Retrograde Cholangiopancreatography (ERCP) with Spyglass assistance. ERCP successfully retrieved a large calculus containing two Hem-o-lok clips. Clip migration leading to stone formation can occur at any time, but is commonly reported within two years post-surgery. Hem-o-lok migration causing CBD lithiasis is a complication that warrants close surveillance; most cases necessitate endoscopic or surgical intervention for management.

Article Details

References

1. Ng DYL, Petrushnko W, Kelly MD. Clip as Nidus for Choledocholithiasis after Cholecystectomy-Literature Review. JSLS. 2020;24(1):e2019.00053. doi:10.4293/JSLS.2019.00053
2. Kou K, Liu X, Hu Y, et al. Hem-o-lok clip found in the common bile duct 3 years after laparoscopic cholecystectomy and surgical exploration. J Int Med Res. 2019;47(2):1052-1058. doi:10.1177/0300060518817216
3. Chen GH, Zhu TM, Xu XL, et al. Migration of metal clips into the duodenum after laparoscopic cholecystectomy: A report of two cases. J Int Med Res. 2018;46(6):2458-2460. doi:10.1177/0300060518760714
4. Nagorni EA, Kouklakis G, Tsaroucha A, et al. Post-laparoscopic cholecystectomy Mirizzi syndrome induced by polymeric surgical clips: a case report and review of the literature. J Med Case Reports. 2016;10(1):135. doi:10.1186/s13256-016-0932-5
5. Hong T, Xu XQ, He XD, et al. Choledochoduodenal fistula caused by migration of endoclip after laparoscopic cholecystectomy. World Journal of Gastroenterology. 2014;20(16):4827-4829. doi:10.3748/wjg.v20.i16.4827
6. Chong VH, Chong CF. Biliary Complications Secondary to Post-Cholecystectomy Clip Migration: A Review of 69 Cases. Journal of Gastrointestinal Surgery. 2010;14(4):688-696. doi:10.1007/s11605-009-1131-0
7. T O, L V, K V den D, et al. Common bile duct foreign body: an unusual case. Surg Laparosc Endosc. 1992;2(1):8-10.
9. Onghena T, Vereecken L, den Dwey KV, et al. Common Bile Duct Foreign Body: An Unusual Case. Surgical Laparoscopy Endoscopy & Percutaneous Techniques. 1992;2(1):8.
9. Hamid HKS, Fullard A, Sabahi J, et al. Late biliary endoclip migration after laparoscopic cholecystectomy: Case report and literature review. International Journal of Surgery Case Reports. 2020;74:205-208. doi:10.1016/j.ijscr.2020.08.027
10. Wu X, Yan H, Zhao S, et al. Clip migration complicated by choledocholithiasis after laparoscopic biliary surgery: a report of four cases. J Int Med Res. 2023;51(8):03000605231190766. doi:10.1177/03000605231190766
11. Tanimu S, Coombs RA, Tanimu Y, et al. Cholecystectomy clip-induced biliary stone: Case report and literature review. Journal of Minimal Access Surgery. 2025;21(3):306. doi:10.4103/jmas.jmas_323_23
12. Europe PMC. Iatrogenic biliary stone. Accessed June 29, 2024. https://europepmc.org/article/med/16525967
13. Cetta F, Baldi C, Lombardo F, et al. Migration of Metallic Clips Used During Laparoscopic Cholecystectomy and Formation of Gallstones Around Them: Surgical Implications from a Prospective Study. Journal of Laparoendoscopic & Advanced Surgical Techniques. 1997;7(1):37-46. doi:10.1089/lap.1997.7.37
14. Wu X, Yan H, Zhao S, et al. Clip migration complicated by choledocholithiasis after laparoscopic biliary surgery: a report of four cases. J Int Med Res. 2023;51(8):03000605231190766. doi:10.1177/03000605231190766
15. Trần Bảo Long, Đoàn Thanh Tùng. Nghiên cứu phẫu thuật cắt túi mật nội soi không dùng clip. Tạp chí Y học Việt Nam. 2006;(9):25-3.