Kết quả phẫu thuật lồng ruột do Polyp Peutz-Jeghers ở trẻ em

Abstract

Peutz–Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by hamartomatous polyps predominantly located in the small intestine, which may lead to intussusception or anemia secondary to gastrointestinal bleeding. The primary therapeutic goal is maximal polyp clearance to reduce complication risk. Although some centers have adopted minimally invasive approaches such as capsule endoscopy or double-balloon enteroscopy, many institutions still rely on open surgery. This retrospective study conducted at Vietnam National Children Hospital (2019 – 2024) included 13 children with PJS who presented with intussusception requiring operative management. The median age was 5 years old, and six patients had a positive family history. Four children underwent emergency surgery and nine underwent urgent procedures. Intraoperatively, all polyps larger than 15mm were removed through enterotomy, with up to eight polyps excised per patient, all without postoperative complication. During a mean follow-up of 43 months, five recurrences were recorded (median 15 months), all of which were successfully managed surgically. Open surgery remains a safe and effective option where advanced endoscopic techniques are limited; however, the recurrence rate highlights the need for long-term surveillance and the development of less invasive strategies.