Bone mineral density in patients with metabolic syndrome and its related factors
Main Article Content
Abstract
Metabolic syndrome (MetS) comprises visceral obesity, reduced HDL-C, elevated blood glucose, increased triglycerides, and hypertension. These abnormalities may influence bone metabolism through multiple mechanisms. This study aimed to evaluate bone mineral density (BMD) in patients with MetS and its related factors. A total of 106 patients with MetS and 105 controls were enrolled at Vinmec Da Nang Hospital from April 2024 to May 2025. BMD at the femoral neck and lumbar spine was measured using dual-energy X-ray absorptiometry (DXA). Clinical characteristics, metabolic parameters, and fracture risk were analyzed. Patients with MetS had significantly lower BMD at both the femoral neck and lumbar spine compared with controls (p < 0.001). The prevalence of osteoporosis in the MetS group was nearly three times higher than in the control group (27.4% vs 10.5%). Based on aforementioned results, we recommend screening and early management of bone health for MetS patients.
Article Details
Keywords
Bone mineral density, metabolic syndrome, DXA
References
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