Các yếu tổ ảnh hưởng đến kết quả tiêm Corticosteroid nội khớp trong điều trị viêm khớp cổ chân do gút cấp

Abstract

Intra-articular corticosteroid injection is an effective treatment for acute gouty ankle arthritis. However, treatment responses vary among patients. Our study included 34 patients with acute gouty ankle arthritis who received intra-articular corticosteroid injections. Factors influencing recurrence rates after corticosteroid injection were analyzed, including: personality characteristics, underlying disease, inflammatory markers, and metabolic disorders. Patients with dyslipidemia, elevated CRP-hs, and leukocytosis showed a negative linear correlation with improvement in VAS scores (p < 0.05). Patients with a leukocyte count > 10 G/L had a 7.8 times higher risk of gout recurrence compared to the non-leukocytosis group. Patients with CRP-hs ≥ 36.2 mg/L had a 2.7 times higher risk of recurrence after corticosteroid injection compared to the group with CRP-hs < 36.2 mg/L (OR = 2.7; p > 0.05). Evaluating the factors influencing treatment outcomes contributes to improving intervention effectiveness and reducing recurrence after intra-articular corticosteroid injections.