Pregnancy outcomes and factors associated with severe features among women with early-onset preeclampsia at Hanoi Obstetrics and Gynecology Hospital

Dang Van Tot, Vu Van Du, Mai Trong Hung, Ho Thi Trang, Nguyen Thi Hang

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Abstract

This study aimed to describe pregnancy outcomes in women with early-onset preeclampsia and to analyze several factors associated with severe preeclampsia in this group of patients. A retrospective cross-sectional study was conducted on 216 patients with early-onset preeclampsia (< 34 weeks of gestation) treated at Hanoi Obstetrics and Gynecology Hospital from 2021 to 2025. The results showed that the mean maternal age was 32.5 ± 5.2 years old, and the mean gestational age at admission was 30.4 ± 2.6 weeks; fetal growth restriction was 37.0%. The cesarean section rate was high (94.4%), most cases delivered before 34 weeks gestation (81.9%), and the median birth weight was 1400 g. Multivariable logistic regression analysis showed that proteinuria ≥ 3 g/l was an independent factor associated with preeclampsia with severe features (aOR = 1.86; 95% CI: 1.04 – 3.31). Early-onset preeclampsia is associated with a high rate of preterm birth and maternal complications, and proteinuria may be a useful indicator of disease severity in clinical practice.

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References

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