Prognostic value of the clinical respiratory score in predicting oxygen therapy outcomes in children with bronchiolitis associated respiratory failure

Trinh Huy Hoang, Truong Van Quy, Quang Anh Diep, Dau Viet Hung

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Abstract

The aim of this study was to evaluate the value of the Clinical Respiratory Score (CRS) in classifying disease severity and predicting oxygen therapy outcomes in children with bronchiolitis associated respiratory failure. A prospective descriptive study was conducted on 87 children aged ≤ 24 months old treated at the Agricultural General Hospital from July 2025 to April 2026. CRS was assessed at the initiation of oxygen therapy (CRS1) and after 1 hour of treatment (CRS2). Prognostic performance was evaluated using receiver operating characteristic (ROC) curve analysis. The median age was 10 months old (IQR: 4 – 16 months), with a male to female ratio of 1.3:1. CRS significantly decreased after 1 hour of treatment (p < 0.001), while both CRS1 and CRS2 were significantly higher in the treatment failure group (p < 0.001). A CRS1 threshold ≥ 7 predicted oxygen therapy failure with an AUC of 0.913 (95% CI: 0.837 – 0.988), sensitivity of 100%, and specificity of 73.4%. The CRS may serve as a useful tool for severity classification and prognostic assessment in children with bronchiolitis associated respiratory failure.

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References

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