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Published: 2022-10-11
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DOI: https://doi.org/10.52852/tcncyh.v158i10.1070
Issue
Vol. 158 No. 10 (2022)
Section
Các bài báo
How to Cite
Nghĩa, N. T., Hoa, N. Q. ., Hằng, N. T. T., & Quỳnh, Đặng T. (2022). 6. Initial evaluation on the clinical therapeutic efficacy of pt powertrim capsules in treating dyslipidemia. Journal of Medical Research, 158(10), 45-54. https://doi.org/10.52852/tcncyh.v158i10.1070

6. Initial evaluation on the clinical therapeutic efficacy of pt powertrim capsules in treating dyslipidemia

Nguyen Tuan Nghia, Ngo Quynh Hoa, Nguyen Thi Thu Hang, Dang Truc Quynh

Main Article Content

Abstract

This study was conducted to evaluate the therapeutic effects of PT Powertrim capsules on dyslipidemia patients. 90 patients diagnosed with dyslipidemia were enrolled in this study and were treated with PT Powertrim in 60 days. The study design was a prospective, uncontrolled interventional clinical study, comparing before and after treatment. After 60 days of treatment, PT Powertrim capsules significantly decreased the serum lipid levels (TC, TG, LDL-C, nonHDL-C) compared to those at before treatment (p < 0.01); the overall treatment efficacy categorized by modern medicine was 28.89% good, 58.89% moderate. From the findings of the study, PT Powertrim capsules posed good efficacy in treating dyslipidemia patients.

Article Details

Keywords

Dyslipidemia, PT Powertrim, traditional medicine

References

1. World Health Organization. Noncommunicable diseases [Fact sheets]. Retrieved from https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases; Assessed June 15th, 2022.
2. Nguyễn Quốc Anh, Ngô Quý Châu. Rối loạn lipid máu. Hướng dẫn chẩn đoán và điều trị bệnh nội khoa. Nhà xuất bản Y học; 2018: 220 - 225.
3. Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020; 41(1): 111 - 188. doi:10.1093/eurheartj/ehz455.
4. Zhao SP, Lu GP, Zhao D, et al. 2016 Chinese guidelines for the management of dyslipidemia in adults. J Geriatr Cardiol JGC. 2018; 15(1): 1 - 29. doi:10.11909/j.issn.1671-5411.2018.01.011
5. Nguyễn Nhược Kim. Bệnh học nội khoa y học cổ truyền. Nhà xuất bản Y học. 2012; 215-218.
6. Đỗ Tất Lợi. Những cây thuốc và vị thuốc Việt Nam. Nhà xuất bản Y học; 2004: 121, 289 - 291, 355, 384, 691, 783, 831, 862.
7. Dương Hồng Quân. Đánh giá hiệu quả điều trị hội chứng rối loạn lipid máu của bài thuốc “Vị linh thang”. Luận văn thạc sỹ y học. Trường Đại học Y Hà Nội; 2019.
8. Hu R, Guo W, Huang Z, et al. Extracts of Ganoderma lucidum attenuate lipid metabolism and modulate gut microbiota in high-fat diet fed rats. J Funct Foods. 2018;46: 403 - 412. doi:10.1016/j.jff.2018.05.020.
9. Wang M, Wang F. Wang Y, et al. Metabonomics Study of the Therapeutic Mechanism of Gynostemma pentaphyllum and Atorvastatin for Hyperlipidemia in Rats. PLOS ONE. 2013; 8(11): e78731.
10. Du H, You JS, Zhao X, et al. Anti-obesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet. J Biomed Sci. 2010; 17, S42.
11. Kwok CY, Li C, Cheng HL, et al. Cholesterol lowering and vascular protective effects of ethanolic extract of dried fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in diet-induced hypercholesterolaemic rat model. J Funct Foods. 2013; 5(3): 1326 - 1335.
12. Rahman S, Begum H, Rahman Z, et al. Effect of cinnamon (Cinnamomum cassia) as a lipid lowering agent on hypercholesterolemic rats. J Enam Med Coll. 2013; 3(2): 94 - 98.
13. Du YZ, Su J, Yan MQ, et al. Improvement effect and mechanism of ethanol extract from Citri Reticulatae Pericarpium on triglyceride in hyperlipidemia model rat. Zhongguo Zhong Yao Za Zhi China J Chin Mater Medica. 2021; 46(1): 190 - 195. doi:10.19540/j.cnki.cjcmm.20200915.408.
14. 郑楚,杨冬业, 徐勤, 韦桂宁. 三七花总皂苷对动脉粥样硬化模型大鼠血脂及血液流变学影响. 中国实验方剂学杂志; 2010(12): 162-164.
15. Trịnh Chu, Dương Đông Nghiệp, Từ Cần, Vi Quế Ninh. Tác dụng của saponin hoa Tam thất trên lipid máu và huyết học của mô hình xơ vữa động mạch. Tạp chí về các công thức Y học cổ truyền thực nghiệm Trung Quốc. 2010(12): 162 - 164.
16. International Camellia Society. International Camellia Journal. 2013.
17. Mallick N, Khan RA. Antihyperlipidemic effects of Citrus sinensis, Citrus paradisi, and their combinations. J Pharm Bioallied Sci. 2016; 8(2): 112-118. doi:10.4103/0975-7406.171727.