16. Comparing oocyte and embryo quality between low dose and high dose conventional ovarian stimulation
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Abstract
This study assessed the effectiveness of low dose and high dose conventional GnRH - antagonist protocols for ovarian stimulation in a group of patients with diminished ovarian reserve. Total oocyte and MII obtained in the low dose regimen of ovarian stimulation group was significantly lower than that in high dose regimen group (3.92 ± 2.33 and 2.86 ± 2.17 versus 5.90 ± 2.29 and 4.26 ± 2.14). Similarly, the number of day 2 embryos in the low dose regimen was also less than that of the high dose regimen (3.38 ± 1.99 versus 4.08 ± 1.76 embryos), but there was no difference in number of type 1 embryos between these two regimens. There was no significant difference in pregnancy, clinical pregnancy and on-going pregnancy rate between two regimens. Low dose regimen of ovarian stimulation showed similar results to high dose regimen and is a viable option for patients with diminished ovarian reserve.