24. Prognostic severe factors in type 2 diabetes with covid-19 patients
Main Article Content
Abstract
This cross-sectional study assessed the prognostic factors in patients with type 2 diabetes mellius (T2DM) with COVID-19 at Hoang Mai Hospital. The study was conducted from November 2021 to March 2022 with 241 patients with type 2 diabetes mellius and COVID-19. The overall mortality rate of patients with COVID-19 was 10.3%. Among 241 patients with type 2 diabetes mellius in our study, the mortality rate was 24.1%. The mortality rate of the diabetic group was significantly higher than that of the non-diabetic group. At the time of admission, those with severe COVID-19 symptoms had higher levels of blood glucose, HbA1c, neutrophils, ferritin, serum creatinine, D-dimer, and Crp-hs, and higher chest X-ray SI score and higher pulse rate than Those with mild or moderate symptoms. The severe symptom group also had lower SpO2 and lymphocyte counts. Patients with severe COVID-19 symptoms needed higher doses of oxygen therapy. Those who had blood sugar controlled using an electric syringe had a higher proportion of severe patients than the group that controlled blood sugar by other methods. The vaccinated group had a lower proportion of severe and critical patients than the non-vaccinated group.
Article Details
Keywords
Type 2 diabtes mellius, COVID-19, prognosis
References
Available onlineat: https://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020.
2. https://www.who.int/data/stories/global-excess-deaths-associated-with-Covid-19-january-2020-december-2021.
3. B. K. Tripathi and A. K. Srivastava, Diabetes mellitus: complications and therapeutics: Medical Science Monitor. International Medical Journal of Experimental and Clinical Research. 2006; 12(7): 130-47.
4. Scheen AJ, Marre M, Thivolet C. Prognostic factors in patients with diabetes hospitalized for COVID-19: Findings from the CORONADO study and other recent reports. Diabetes Metab. 2020; 46(4): 265-271. doi: 10.1016/j.diabet.2020.05.008. Epub 2020 May 21. PMID: 32447101; PMCID: PMC7241378.
5. S. Roy, T. Mazumder, and S. Banik, The association of cardiovascular diseases and diabetes mellitus with COVID-19 (SARS-CoV-2) and their possible mechanisms, SN comprehensive clinical medicine. 2020; 25: 1-6.
6. Hướng dẫn chẩn đoán và điều trị COVID-19. Hướng dẫn chẩn đoán và điều trị COVID-19. Accessed November 4, 2022. https://vncdc.gov.vn/huong-dan-chan-doan-va-dieu-tri-covid-19-nd16851.html7. H.Poaty, G.E. Poaty. Diabetes and COVID-19 in Congolese patients. Afr Health Sci. 2021 21(3): 1100–1106. doi: 10.4314/ahs.v21i3.18
8. Y.Chen, D.Yang. Clinical characteristics and outcomes of patients with diabetes and Covid-19 in association with glucose-lowering medication.
9. N.Zhang, C.Wang. Risk factors for poor outcomes of diabetes patients with COVID-19: a single-center, retrospective study early outbreak in China, Front. Endocrinol. 2020 | https://doi.org/10.3389/fendo.2020.571037.
10. Peric Slobodan, Stulnig Thomas M. Diabetes and COVID-19. Disease-Management-People. Wien Klin Wochenschr. 2020: 1-6.
11. Akbariqomi Mostafa, Hosseini Mahboobeh Sadat, Rashidiani Jamal, Sedighian Hamid, Biganeh Hossein, Heidari Reza, et al. Clinical characteristics and outcome of hospitalized COVID-19 patients with diabetes: A single-center, retrospective study in Iran. Diabetes Res Clin Pract. 2020; 169: 108467.
12. Pinto Lana C, Bertoluci Marcello C. Type 2 diabetes as a major risk factor for COVID-19 severity: a meta-analysis. Arch Endocrinol Metab. 2020; 64(3): 199–200.
13. Pal Rimesh, Bhansali Anil. COVID-19, diabetes mellitus and ACE2: The conundrum. Diabetes Res Clin Pract. 2020; 162: 108132.