26. Results of synovial biopsy in diagnosis of some common arthropathies

Vuong Thu Ha, Bui Van Lenh, Le Tuan Linh, Doan Tien Luu, Dang Thi Bich Nguyet, Pham Xuan Thanh

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Abstract

This study aims to evaluate the safety and effectiveness of ultrasound-guided synovial biopsy in diagnosing of some common joint diseases in 49 patients. A cross-sectional descriptive study was conducted from November 2019 to May 2022. Results showed synovial biopsy was an easy procedure to perform in most patients. Most (91.8%) of patients reported no or little pain during the procedure. Synovial biopsy was also a safe procedure with few complications; the rate of bleeding complications at the needle puncture site was 8.2% (4/49 cases); and the rate of intra-articular bleeding was 2%. There was no serious complications such as puncture site infection, joint infection, neurological and vascular complications. The technique was successfully performed in 98% of the patients. The synovial membrane biopsy specimens were subsequently taken for histopathology, bacterial cultures and PCR for tuberculosis. The results of these tests led to confirmation of diagnosis in 65,3% of cases, and the concordance between synovial biopsy results with the final diagnosis was 98%.


The synovial membrane biopsy specimens were taken for histopathology, bacterial cultures and PCR for tuberculosis, the results of these tests allow the diagnosis to be confirmed in 65,3% of cases and the concordance between synovial biopsy results with the final diagnosis was 98%. In cases with confirmed diagnosis of joint infection, synovial membrane biopsy showed positive bacterial culture or purulent histopathology in 92.8%, thus the sensitivity of synovial biopsy in the diagnosis of joint infections is very high.

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