12. The relationship between testosterone deficiency and BMI and lipid disorder in men

Nguyen Hoai Bac, Dinh Huu Viet, Tran Van Kien

Main Article Content

Abstract

Functional hypogonadism, characterized by low testosterone levels and corresponding clinical symptoms, is associated with age and metabolic disorders, especially lipid disorders. We studied 1104 males treated at the Department of Andrology and Sexual Medicine - Hanoi Medical University Hospital to evaluate the association between functional hypogonadism and BMI and lipid disorder. The prevalence of testosterone deficiency was 24.5% (271/1104). The mean age of the subjects was 30.04 ± 6.05 years old and the mean BMI was 23.39 ± 2.84 kg/m2; 54.98% were overweight or obese (BMI ≥ 23 kg/m2). Age, BMI and triglyceride levels were negatively correlated with testosterone levels (p < 0.001). Males over 35 years old had a 3.43-time higher risk of testosterone deficiency than the younger males (pOR = 3.43; p < 0.001) and obese males had a 3.5 times higher risk of hypogonadism than normal weight males (pOR = 3.5; p < 0.001). In summary, age and obesity are risk factors for testosterone deficiency. In practice, clinicians should screen for hypogonadism in overweight and obese men, especially in the elderly group.

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References

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