38. Neonatal dengue with meningitis: A case report

Pham Thi Que, Nguyen Van Lam, Do Thien Hai

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Abstract

Neonatal Dengue is a rare condition with atypical clinical features, easily misdiagnosed with other diseases. Neonates infected with Dengue virus may be asymptomatic or have severe even fatal complications. We reported a case of a 7-day-old female infant whose mother had Dengue fever 1 day before delivery; clinical manifestations including fever, macular erythema, hepatomegaly, thrombocytopenia, and positive Dengue NS1 antigen from day 2 of the disease. This infant had meningitis complicated by Dengue virus with presentations of lethargy, poor feeding, slightly bulging fontanel, cerebrospinal fluid pleocytosis, presence of Dengue IgM and IgG antibodies in the blood and cerebrospinal fluid, and normal cranial MRI. After treatment, the patient was stable. Conclusion: Newborns born to mothers with Dengue fever should be monitored to avoid missed diagnoses, and clinical manifestations of neonatal Dengue fever include fever, hepatomegaly, rash, and thrombocytopenia.

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References

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