8. Results of glycemic control with Insulin infusion among severe stroke patients

Ha Tan Duc, Pham Thu Thuy, Nguyen Thi Ngọc Han

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Abstract

Achieving glycemic control is related partially to the outcomes in stroke patients. We conducted an interventional study on severe stroke patients admitted to the Can Tho Central General Hospital. Insulin infusion was used to control blood glucose levels in nine-teen patients with persistent hyperglycemia according to the Cleveland intensive care unit protocol, and we evaluated the glycemic control. The median blood glucose concentration achieved before and after insulin infusion on glycemic control was 281 mg/dL (IQR: 231 - 317) and 168 mg/dL (IQR: 156 - 175), respectively, with minimizing glycemic fluctuation. The target blood level was reached by 78.9% of patients, and one patient had hypoglycemia. The proportion of non-survivors was 63.2%. Despite achieving the target blood glucose level, most patients experienced low hypoglycemia when using this protocol. Nevertheless, patients who suffered a severe stroke had a relatively high mortality.

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