12. Role of ultrasonography in the diagnosis, grading and treatment of cesarean-section scar pregnancy

Do Van Quyet, Luong Minh Tuan, Pham Hong Duc

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Abstract

Our aim is to evaluate the role of ultrasonography in the diagnosis, grading and treatment of cesarean-section scar pregnancy (CSP). The study included 66 patients, average age 35 ± 4.9 (24 - 45). The cases encountered in grades II, III, and IV were: 42 (63.6%), 18 (27.2%), and 6 (9.1%). The mean indices of gestational age, gestational sac size, residual uterine muscle thickness, and blood loss due to termination of pregnancy differed between classes on SA (p < 0.05). Methods of abortion depend on the grade of CSP, with additional invasive treatment corresponding to a higher grade. Grade II is primarily embryo aspiration alone or in combination with balloon insertion. If there is a fetal heart rate in grade II, MTX should be used before aspiration. If it is rich in blood vessels in grade III, it should be embolized before aspiration. In contrast, grade IV requires open surgery, switching to open surgery when aspiration fails. Notably, the embolization cases prior to aspiration, even at grade III, did not necessitate surgery, and the blood loss was minimal. Hence, ultrasound is noteworthy in assessing the lesions and the classification of CSP, which is useful for deciding an appropriate and effective treatment method for each patient.

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References

1. Rotas MA, Haberman S, Levgur M. Cesarean Scar Ectopic Pregnancies: Etiology, Diagnosis, and Management. Obstetrics & Gynecology. 2006; 107(6): 1373-1381. doi:10.1097/01.AOG.0000218690.24494.ce.
2. Jurkovic D, Hillaby K, Woelfer B, Lawrence A, Salim R, Elson CJ. First-trimester diagnosis and management of pregnancies implanted into the lower uterine segment Cesarean section scar. Ultrasound Obstet Gynecol. 2003; 21(3): 220-227. doi:10.1002/uog.56.
3. Cheng PJ, Chueh HY, Soong YK. Sonographic diagnosis of a uterine defect in a pregnancy at 6 weeks’ gestation with a history of curettage. Ultrasound Obstet Gynecol. 2003; 21(5): 501-503. doi:10.1002/uog.109.
4. Jordans IPM, Verberkt C, Leeuw RAD, et al. Definition and sonographic reporting system for Cesarean scar pregnancy in early gestation: modified Delphi method. Ultrasound in Obstetrics & Gynecology. 2022; 59(4): 437-449. doi:10.1002/uog.24815.
5. Pristavu A, Vinturache A, Mihalceanu E, Pintilie R, Onofriescu M, Socolov D. Combination of medical and surgical management in successful treatment of caesarean scar pregnancy: a case report series. BMC Pregnancy Childbirth. 2020; 20(1): 617. doi:10.1186/s12884-020-03237-8.
6. Gonzalez N, Tulandi T. Cesarean Scar Pregnancy: A Systematic Review. Journal of Minimally Invasive Gynecology. 2017; 24(5): 731-738. doi:10.1016/j.jmig.2017.02.020.
7. Junaid D, Chaudhry S, Usman M, Hussain R. CAESAREAN SCAR ECTOPIC PREGNANCY: A CASE SERIES. Pakistan Journal of Medicine and Dentistry. 2018; 7(3): 4-4. doi:10.36283/pjmd.v7i3.166.
8. Chiang YC, Tu YA, Yang JH, Lin SY, Lee CN, Shih JC. Risk factors associated with failure of treatment for cesarean scar pregnancy. Int J Gynaecol Obstet. 2017; 138(1):28-36. doi:10.1002/ijgo.12157.
9. Timor-Tritsch IE, Khatib N, Monteagudo A, Ramos J, Berg R, Kovács S. Cesarean scar pregnancies: experience of 60 cases. J Ultrasound Med. 2015; 34(4): 601-610. doi:10.7863/ultra.34.4.601.
10. Timor-Tritsch IE, Monteagudo A, Bennett TA, Foley C, Ramos J, Agten AK. A new minimally invasive treatment for cesarean scar pregnancy and cervical pregnancy. American Journal of Obstetrics & Gynecology. 2016; 215(3): 351.e1-351.e8. doi:10.1016/j.ajog.2016.03.010.
11. Lin SY, Hsieh CJ, Tu YA, et al. New ultrasound grading system for cesarean scar pregnancy and its implications for management strategies: An observational cohort study. PLoS One. 2018; 13(8): e0202020. doi:10.1371/journal.pone.0202020.
12. Elito Júnior J, Araujo Júnior E, Martins Santana EF, et al. Uterine artery embolization with methotrexate infusion as treatment for cesarean scar pregnancy. Case report. Med Ultrason. 2013; 15(3): 240-243. doi:10.11152/mu.2013.2066.153.jej1eaj2.
13. Heidar Z, Zadeh Modarres S, Abediasl Z, Khaghani A, Salehi E, Esfidani T. Cesarean scar pregnancy treatment: a case series. J Med Case Rep. 2021; 15:506. doi:10.1186/s13256-021-03081-0.
14. Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, et al. Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2018; 51(2): 169-175. doi:10.1002/uog.17568.
15. Việt TQ, Cường TD, Trang NTH, Định TT, Hảo NTX. Thái độ xử trí thai làm tổ vết mổ cũ dựa trên hình ảnh siêu âm tại Khoa Phụ ngoại Bệnh viện Phụ sản Trung ương từ 01/2021 - 6/2021. 1. 2021; 19(4): 09-14. doi:10.46755/vjog.2021.4.1336.
16. T J, G L, L H, H M, S Z. Methotrexate therapy followed by suction curettage followed by Foley tamponade for caesarean scar pregnancy. European journal of obstetrics, gynecology, and reproductive biology. 2011; 156(2). doi:10.1016/j.ejogrb.2011.01.016.
17. Gu Z, Jia P, Gao Z, Gu W, Zhao H, Zhao S. Uterine artery embolization combined with ultrasound-guided dilation and curettage for the treatment of cesarean scar pregnancy: Efficacy and 5–8-year follow-up study. Journal of Interventional Medicine. Published online March 18, 2022. doi:10.1016/j.jimed.2022.03.006.
18. Bohiltea R, Ducu I, Mihai B, et al. Uterine Artery Embolization Combined with Subsequent Suction Evacuation as Low-Risk Treatment for Cesarean Scar Pregnancy. Diagnostics (Basel). 2021; 11(12): 2350. doi:10.3390/diagnostics11122350.