5. Results of auricular acupressure therapy combined with PPIs in patients with gastroesophageal reflux disease

Nguyen Thi Thanh Tu, Nguyen Thi Ngoc Linh

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Abstract

The study was conducted to evaluate the results of auricular acupressure therapy (using Semen Vasccariae) combined with PPIs in patients with gastroesophageal reflux disease. The study was designed as a controlled clinical intervention study, comparing patients’ condition before and after treatments. Sixty patients who were diagnosed with gastroesophageal reflux disease with similarity in age, gender, duration of disease, and degree of reflux according to the GERD-Q scale were divided int0 two groups. The study group was treated with auricular acupressure by using Semen Vasccariae combined with oral Lomec (Omeprazol) at 20 mg/day, the control group was administered with Lomec (Omeprazol at 40 mg/day for 30 days. The results showed that in each of both groups, the mean score of symptoms of gastroesophageal reflux disease and the mean score of GERD-Q decreased significantly while comparing the before treatment with the after treatment (p < 0.05) and there was no difference between the two groups (p > 0.05). As such we concluded that a low dose of Omeprazole combined with auricular acupressure treatment achieved equivalent improved symptoms as with a higher dose of Omeprazole.

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References

1. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Gastroesophageal Reflux (GER) and Gastroesophageal Reflux Disease (GERD) in Adults. Published October 5, 2016. Accessed April 29, 2021. https://web.archive.org/web/20161005041548/https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ger-and-gerd-in-adults/Pages/all-content.aspx
2. El-Serag HB, Sweet S, Winchester CC, et al. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63(6):871-880. doi:10.1136/gutjnl-2012-304269
3. Sifrim D, Zerbib F. Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors. Gut. 2012;61(9):1340-1354. doi:10.1136/gutjnl-2011-301897
4. Sigterman KE, Pinxteren B van, Bonis PA, et al. Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev. 2013;(5). doi:10.1002/14651858.CD002095.pu b5
5. Cho JH, Shin CM, Yoon H, et al. Efficacy of a high-dose proton pump inhibitor in patients with gastroesophageal reflux disease: a single center, randomized, open-label trial. BMC Gastroenterol. 2020;20(1):275. doi:10.1186/s1 2876-020-01410-z
6. Haastrup PF, Thompson W, Sondergaard J, et al. Side effects of long-term proton pump inhibitor use: A review. Basic Clin Pharmacol Toxicol. 2018;123(2):114-121. doi:10.1111/bcpt. 13023
7. Li D, Zhu L, Liu D. Acupuncture for refractory gastro-oesophageal reflux disease: a systematic review and meta-analysis protocol. BMJ Open. 2019;9(8):e030713. doi:10.1136/bmjopen-2019-030713
8. Hosseinkhani A, Lankarani KB, Mohagheghzadeh A, et al. An Evidence-based Review of Medicinal Herbs for the Treatment of Gastroesophageal Reflux Disease (GERD). Curr Drug Discov Technol. 2018;15(4):305-314. doi:10.2174/1570163814666171010113517
9. Ling HW. Traditional chinese medicine in the treatment of gastroesophageal reflux in newborns. Journal of Health and Medical Research. 2020;11:3. https://www.iomcworld.org/abstract/traditional-chinese-medicine-in-the-treatment-of-gastroesophageal-reflux-in-newborns-60848.html
10. Mostafa R. Rome III: The functional gastrointestinal disorders, third edition, 2006. World J Gastroenterol WJG. 2008;14(13):2124-2125. doi:10.3748/wjg.14.2124
11. Sami S, Ragunath K. The Los Angeles classification of gastroesophageal reflux disease. Video J Encycl GI Endosc. 2013;1(1):103-104. doi:10.1016/S2212-0971(1 3)70046-3
12. Terry Oleson. The Amazing Science of Auriculotherapy. Pain Relief, Smoking Cessation, Weight Loss and the Healing of 350 Diseases through Ear Acupressure. Published 2011. Accessed May 9, 2021. https://www.scribd.com/document/207220940/The-Amazing-Science-Of-Auriculotherapy
13. Carter K, Olshan-Perlmutter M. NADA protocol: integrative acupuncture in addictions. J Addict Nurs. 2014;25(4):182-187; quiz 188-189. doi:10.1097/JAN.0000000000000045
14. Wang L, Yang J, Zhao B, et al. The similarities between the World Federation of Acupuncture-Moxibustion Societies’ standards for auricular acupuncture points and the European System of Auriculotherapy Points according to Nogier and Bahr. Eur J Integr Med. 2016;8(5):817-834. doi:10.1016/j.eujim.2016.06.011
15. Dent J, Jones R, Vakil N, et al. A management strategy for GERD based on the Gastroesophageal reflux disease questionnaire (GerdQ). Scand J Gastroenterol. 2008;43:34-35.
16. Hetzel DJ, Dent J, Reed WD, et al. Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology. 1988;95(4):903-912. doi:10. 1016/0016-5085(88)90162-x
17. Landgren K. Chapter 6 - The ear: its parts and acupuncture points. In: Landgren K, ed. Ear Acupuncture. Churchill Livingstone; 2008:55-68. doi:10.1016/B978-044306899-7.5 0007-9
18. 刘淑兰. 耳针治疗重症呃逆(膈肌痉挛)47例. 中国针灸. 1984;7(2):46.
Lưu Thục Lan. Châm cứu điều trị 47 trường hợp nấc nặng do cơ thắt cơ hoành. Châm cứu Trung Quốc. 1984;7(2):46.
19. Nguyễn Nhược Kim, Nguyễn Thị Thu Hà. Bệnh học nội khoa Y học cổ truyền. Nhà xuất bản Y học; 2017.
20. 赵萌生. 点天鼎穴治疗顽固性呃逆20例. 吉林中医药. 1986;4:16.
Triệu Manh Sinh. Điều trị 20 trường hợp nấc nặng bằng phương pháp bấm huyệt tai. Y học cổ truyền Cát Lâm Trung Quốc. 1986;4:16.
21. Tan Y, Zhao Y, He T, et al. Efficacy and safety of auricular point acupressure treatment for gastrointestinal dysfunction after laparoscopic cholecystectomy: study protocol for a randomized controlled trial. Trials. 2016;17(1):280. doi:10.1186/s13063-016-1404 -3
22. Chung VCH, Wong CHL, Ching JYL, et al. Electroacupuncture plus standard of care for managing refractory functional dyspepsia: protocol of a pragmatic trial with economic evaluation. BMJ Open. 2018;8(3):e018430. doi:10.1136/bmjopen-2017-018430
23. Zhu J, Guo Y, Liu S, et al. Acupuncture for the treatment of gastro-oesophageal reflux disease: a systematic review and meta-analysis. Acupunct Med J Br Med Acupunct Soc. 2017;35(5):316-323. doi:10.1136/acupm ed-2016-011205