delirium, ventilation, ICU Delirium and associated factors in mechanically ventilated patients at Hanoi Medical University

Dinh Thi Thanh Hue, Tran Thi Ha An, Hoang Bui Hai, Le Ngoc Ha, Nguyen Anh Dung, Le Thi Cuc, Tran Quyet Tien, Do Thi Kim Oanh, Truong Quang Trung, Nguyen Thi Thu Phuong, Nguyen The Tuyen, Vu Thi Lan Anh

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Abstract

Patients with delirium had longer hospital stays and higher 6-month mortality compared with patients without delirium. Identifying, treating and preventing delirium is increasingly considered a priority in the comprehensive health care of intensive care patients because it is a common complication, occurring in up to 80% of patients requiring mechanical ventilation. To supplement the data source on delirium in Vietnam, we conducted this research with 2 goals: describe delirium in mechanically ventilated patients and investigate factors related to delirium in this patient group. This is a cross-sectional descriptive study design of 34/84 mechanically ventilated patients eligible for inclusion in the study over a 6-month period (March to August 2022) at the Department of Emergency Medicine and Intensive Care, University of Medicine Hospital Hanoi. Results showed that the rate of delirium in the study was very high (61.76%), mainly reduced agitation (66.67) and increased agitation (33.33%); median time from hospital admission to delirium was 12.19 ± 12.76 days; time from ICU admission to delirium 6.14 ± 6.41 days; the average length of time spent in ICU was quite high (13.88 ± 8.42 days). The main condition of patients with delirium was infection (42.86%). Demographic characteristics, pathological conditions were not related to delirium. SOFA score, number of days of sedative use were related to delirium with p < 0.05 and odds ratio was OR = 1.42 (95%CI: 1.03 - 1.95) and OR = 1.56 (95%CI: 1.09 - 2.24), respectively. The proportion of mechanical ventilation patients with delirium was high, especially in patients using long-term sedation, so it is necessary to evaluate and closely monitor the delirium in these patients. Additionally, poor pain management and disturbances in the patient's waking sleep cycle also increased the incidence of delirium in ICU patients. Evaluation of the patient's SOFA score for timely intervention and treatment is necessary to ensure patient safety.

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References

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