39. Evaluating the effects of buccal spray solution YHN on an experimental model of acute pharyngitis
Main Article Content
Abstract
This study evaluated the effect of buccal spray solution YHN in a rat model of ammoniac 15%-induced acute pharyngitis. For three days, the acute pharyngitis rats were sprayed with the test solution at 200µl once a day, or 200µl twice a day, or 200µl Anginovag once a day. The rats underwent pharyngeal endoscopies to evaluate the inflammatory degrees at pre-treatment, immediately after ammoniac administration, and every day for 3 days following each administration of the buccal spray solution. At the end of the experiment, blood samples were collected to quantify the white blood cells and neutrophils count. Pharyngeal tissue was taken to observe the morphological changes. The results showed that the buccal spray solution YHN displayed an anti-inflammatory effect by significantly decreasing the inflammatory levels estimated by the pharyngeal endoscopic images and pathological changes of pharyngeal tissue. Moreover, the test solution reduced the white blood cells and neutrophils count. Therefore, the buccal spray solution YHN had an anti-inflammatory effect on the rat model of ammoniac 15%-induced acute pharyngitis.
Article Details
Keywords
Buccal spray solution YHN, acute pharyngitis, ammoniac, expeimental
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