37. Red blood cell recovery in allogeneic hematopoietic stem cell transplantation at the Central Institute of Hematology - Blood Transfusion from 2019 to 2022

Nguyen Quang Tung, Do Hong Ngoc

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Abstract

Providing data on red blood cell transplantation time would assists clinicians to prepare large volumes and to be able to make transfusion decisions appropriate to each stage of the transplant. The time and rate of red blood cell recovery in several groups of allogeneic hematopoietic stem cell transplant patients was analyzed in a retrospective case series of 37 patients receiving allogeneic stem cell transplant. Results showed that the mean reticulocyte engraftment of the minor ABO-incompatible group was 12.5 ± 2.2 days. The time for complete transformation into the donor derived - ABO type antigen was 15.3 ± 7.1 weeks. The mean time of RBC transfusion independence was 25 ± 18.2 days in patients receiving major ABO-incompatible transplantation; in the minor ABO-incompatible group it was 16.6 ± 10.2 days. The reticulocyte engraftment time of the major ABO-incompatible group was delayed in the minor ABO-incompatible group. The time for complete transformation into the donor derived - type ABO antigen was not different between the major group and the minor group. The major ABO-incompatible group tended to become RBC transfusion independence later than the minor ABO-incompatible group.

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References

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