11. Evaluating glioma grading: Assessing the value of quantitative magnetic resonance spectroscopy and diffusion tensor imaging
Main Article Content
Abstract
In this study we evaluated the role of magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) in predicting the histological grade of gliomas. The study was conducted on 60 patients with supratentorial glioma who underwent MRI, surgery, and had post-operative pathology results at Viet Duc Hospital from June 2021 to August 2023. The analysis scrutinized the statistical association between the values of Cho/NAA, FA, and MD within both the tumor and peritumoral regions and the histological grade of glioma as determined by post-operative pathology. Notably, the Cho/NAAp ratio and MDp values exhibited statistically significant disparities between lower-grade and higher-grade gliomas. Furthermore, the FAp value demonstrated significant variance between lower-grade and higher-grade gliomas. Combining Cho/NAAp with FAp facilitated enhanced prediction of glioma grade, yielding a sensitivity of 73.7% and a specificity of 95.5%. Additionally, it was observed that Cho/NAA, FA, and MD values within the peritumoral region contributed more effectively to glioma grading compared to those within the tumor region.
Article Details
Keywords
Diffusion-weighted imaging, MR spectroscopy, diffusion tensor imaging, glioma, WHO grading
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