48. Đặc điểm kháng kháng sinh của các vi khuẩn gây nhiễm khuẩn huyết thường gặp tại Bệnh viện Bệnh nhiệt đới Trung ương năm 2022 - 2023

Abstract

The study was conducted to describe the antibiotic resistance characteristics of some common bacteria causing sepsis at the National Hospital of Tropical Diseases from January 2022 to December 2023. During the study period, 117 patients were diagnosed with sepsis, and the bacterial causes were identified. Results: the average age of patients in the study was 56.82 ± 15.92, with males accounting for 66.7%. The primary routes of admission were respiratory 22.2%, skin/soft tissue 10.3%, gastrointestinal 9.4%, and urinary 8.5%. Community-acquired bacteremia was 61.6%, Gram-positive bacteria account for 53.8%. The three most common bacterial pathogens were E. coli (26.5%), S. aureus (23.1%), and K. pneumoniae (12%). Antibiogram results showed that E. coli was 20% - 50% resistant to antibiotics in the Cephalosporin, 25% - 46.9% resistant to antibiotics in the Quinolone group, 7.2% resistant to amikacin and 100% sensitivity to antibiotics in the Carbapenem. K. pneumoniae was 100% resistant to Ampicillin, 6.7% - 13.3% carbapenem resistant, 14.3% - 27.3% cephalosporin resistant, 40% ciprofloxacin resistant, 7.2% amikacin resistant. S. aureus: MRSA was 82.6%, VRA was 3%, 100% resistance to penicillin and 87.1% resistance to clindamycin.