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Published: 2024-10-15
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DOI: https://doi.org/10.52852/tcncyh.v182i9.2668
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Vol. 182 No. 9 (2024)
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Hiếu, Đặng H. ., Trung, V. Q. ., & Hằng, Đào V. . (2024). Accuracy of PSPW index on 24-hour pH-impedance monitoring in the diagnosis of gastroesophageal reflux disease. Journal of Medical Research, 182(9), 62-69. https://doi.org/10.52852/tcncyh.v182i9.2668

Accuracy of PSPW index on 24-hour pH-impedance monitoring in the diagnosis of gastroesophageal reflux disease

Dang Duy Hieu, Vu Quoc Trung, Dao Viet Hang

Main Article Content

Abstract

Our study aimed to evaluate the accuracy of PSPW index on esophageal pH-impedance monitoring in the diagnosis of GERD among Vietnamese patients having suspected reflux symptoms. A cross-sectional descriptive study was conducted among patients having suspected reflux symptoms and underwent 24-hour pH-impedance monitoring at Hoang Long Clinic and the Institute of Gastroenterology and Hepatobillary between March 2020 and February 2023. 112 patients were eligible, the mean age was 45.2 ± 11.9. 34 patients satisfied the diagnostic criteria of GERD, 24 patients had ERD and 10 patients had NERD. There was a significant difference in 24-hour pH impedance metrics between the GERD and non-GERD groups (p < 0.001). PSPW index correlated with Demeester, MNBI, AET scores (p < 0.001) and number of acid refluxes (p = 0.02). The area under the ROC curve (AUC) of PSPW index in GERD diagnosis was 0.72, with sensitivity of 50% and specificity of 83.3%, the optimal cut off value was 22%.

Article Details

Keywords

Gastroesophageal reflux disease, GERD, PSPW, 24-hour pH impedance monitoring

References

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