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Published: 2024-11-11
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DOI: https://doi.org/10.52852/tcncyh.v183i10.2893
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Vol. 183 No. 10 (2024)
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Các bài báo
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Hà, N. T., Dũng, V. C., Mai, T. T. C., & Ngọc, L. T. K. (2024). Contribution of pitutary magnetic resonance imaging in the diagnosis of growth hormone deficiency. Journal of Medical Research, 183(10), 207-216. https://doi.org/10.52852/tcncyh.v183i10.2893

Contribution of pitutary magnetic resonance imaging in the diagnosis of growth hormone deficiency

Nguyen Thu Ha, Vu Chi Dung, Tran Thi Chi Mai, Le Thi Kim Ngoc

Main Article Content

Abstract

Magnetic resonance imaging is a crucial technique for assessing patients suspected of having hypothalamic-pituitary disorders, particularly those with growth hormone deficiency. We outline the features and relationships between pituitary MRI findings and clinical traits in individuals with growth hormone deficiency. This study is based on clinical data and brain MRI assessments of 42 patients with combined growth hormone deficiency (CPHD) and 62 patients with isolated growth hormone deficiency (IGHD) collected between January 2014 and June 2024. Among the CPHD patients, 37 patients exhibited structural abnormalities in the pituitary, including interrupted pituitary stalk syndrome in 6 cases and pituitary hypoplasia in 15 cases. For the IGHD group, 11 patients showed pituitary hypoplasia and one patient had an ectopic posterior pituitary. The majority, 50 out of 62 IGHD patients, presented with a normal pituitary gland. Most CPHD patients had abnormal pituitary structures, while normal MRI results were frequently observed in children with IGHD.

Article Details

Keywords

Pituitary MRI, hypopituitarism, combined growth hormone deficiency, isolated growth hormone deficiency, CPHD, IGHD

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