Assessment of depression in patients with rheumatoid arthritis using the Montgomery-Åsberg scale

Tran Thi Thu Ha, Nguyen Van Hung, Truong Hong Vinh, Lai Thuy Duong, Duong Minh Tam

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Abstract

To describe the prevalence of depressive disorders in patients with rheumatoid arthritis (RA) and identify associated factors, a cross-sectional study was conducted on 187 RA patients. Demographic data and clinical characteristics related to RA were collected. Depression was assessed using the Montgomery-Åsberg Depression Rating Scale (MADRS). The prevalence of depression in this study was 54%, with approximately 25% of patients reporting suicidal ideation. Compared to the non-depressed group, patients with depression had a higher proportion of females and individuals who were single, divorced, or widowed. They also had lower educational attainment and lower income. The depressed group exhibited longer morning stiffness duration, a higher prevalence of joint deformities, and greater disease activity. In logistic regression analysis, female gender was identified as an independent risk factor for depression (OR = 4.84; 95% CI: 1.66 – 16.1; p = 0.006). This study highlights a high prevalence of depression and its association with specific demographic and clinical factors in RA patients. Notably, the 25% prevalence of suicidal ideation underscores the critical need for routine depression and suicide risk screening in clinical practice. Further research with larger sample sizes and a broader assessment of mental health outcomes is warranted to develop appropriate intervention strategies aimed at improving comprehensive care for RA patients.

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References

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