Khả năng gắng sức của bệnh nhân suy tim phân suất tống máu giảm nhẹ và suy tim phân suất tống máu bảo tồn

Abstract

This study was conducted to assess the exercise capacity of patients diagnosed with heart failure with mildly reduced ejection fraction (HFmrEF) and preserved ejection fraction (HfpEF) based on cardiopulmonary exercise testing (CPET) and the 6-minute walk test (6MWT). In a cohort of 40 patients with heart failure and left ventricular ejection fraction (LVEF) > 40%, the mean VO_2max was 13.8 ± 0.5 ml/kg/min, with 47.5% of patients falling below the prognostically significant threshold of 14 ml/kg/min. The mean 6MWT distance was 359.1 ± 8.7 meters, and 10% of patients walked less than 300 meters, indicating significant functional limitation. Inspiratory muscle weakness (IMW) was significantly associated with reduced VO_2max (12.5 vs. 14.3, p = 0.0227) and shorter 6MWT distance (331.6 vs. 373.9 meters, p = 0.0091). In multivariate regression analysis, 6MWT distance was an independent predictor of VO_2max (β = 0.020, p = 0.027). In conclusion, patients with HFmrEF and HFpEF exhibited markedly reduced exercise capacity, reflected in low VO_2max and limited 6MWT distance. These findings highlight the importance of functional assessment for screening and selecting candidates for cardiac rehabilitation programs.