Isolation of Escherichia coli bacteriophage from water environment by lysis method

Nguyen Trong Tue, Vu Duc Anh, Pham Thi Hoa

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Abstract

The World Health Organization (WHO) classifies Vietnam as one of the countries with the highest antibiotic resistance in the world, in which Escherichia coli is also one of the most resistant bacteria. Researchers have sought to use bacteriophages, or phages for short, as an alternative to antibiotics for bacterial infections. Previous studies have shown that phages have cured 90% of chronic viral infections (meningitis, peritonitis, osteomyelitis) in human caused by bacterial pathogens antibiotic resistance such as Staphylococcus aureus, Pseudomonas aeruginosa, E. coli. In Vietnam, the studies on phages are still limited. Our study was conducted with the objective of isolating Bacteriophage from wastewater environment able to degraded E. coli bacteria. Conclusion: successfully isolated bacteriophages, capable of specifically degrading human pathogenic E. coli bacteria from wastewater environment, is a premise for antibiotic resistance therapy in the future.

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References

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