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Published: 2026-03-09
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DOI: https://doi.org/10.52852/tcncyh.v199i2.4584
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Vol. 199 No. 2 (2026)
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Các bài báo
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Tam, V., Ni, T. T. L., & Vân, N. H. T. (2026). Synovial fluid acid uric and synovial fluid-to-serum uric acid ratio in gouty patients. Journal of Medical Research, 199(2), 414-420. https://doi.org/10.52852/tcncyh.v199i2.4584

Synovial fluid acid uric and synovial fluid-to-serum uric acid ratio in gouty patients

Vo Tam, Tran Thi Ly Ni, Nguyen Hoang Thanh Van

Main Article Content

Abstract

A cross-sectional study was conducted on 61 patients with gout to describe synovial fluid uric acid levels, the synovial fluid-to-serum uric acid ratio, and associated factors. Synovial fluid uric acid was consistently higher than serum uric acid (479.75 vs. 424.01 µmol/L; p < 0.001) and showed a marked difference compared with the osteoarthritis group. The mean synovial fluid-to-serum uric acid ratio in gout patients was 1.16 ± 0.18, significantly higher than the osteoarthritis group (0.99 ± 0.08). Synovial fluid uric acid and serum uric acid demonstrated a very strong positive correlation (r = 0.881; p < 0.001), whereas the synovial fluid-to-serum uric acid ratio showed a moderate negative correlation with serum uric acid (r = -0.539; p < 0.001).

Article Details

Keywords

Gout, synovial fluid uric acid, synovial fluid-to-serum uric acid ratio, SSR

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