Đặc điểm tổn thương khớp cùng chậu trên hình ảnh cộng hưởng từ và một số yếu tố liên quan trên bệnh nhân viêm khớp cột sống thể trục

Abstract

Axial spondyloarthritis is a disease with heterogeneous clinical manifestations and is frequently diagnosed at a delayed stage. Magnetic resonance imaging (MRI) is considered as a crucial tool for early diagnosis, monitoring inflammatory activity, and assessing treatment response. With the objective of evaluating sacroiliac joint (SIJ) lesions on MRI, the study yielded the following results: HLA-B27 positivity was observed in 48.9% of cases, and elevated C-reactive protein (CRP) levels were found in 64.4%. MRI findings consistent with sacroiliitis according to the ASAS criteria were identified in 36 out of 45 patients (80%). On average, each patient exhibited 4 out of 12 possible MRI lesion patterns of the sacroiliac joints concurrently. Bone marrow edema was the most prevalent MRI feature, present in 36/45 cases (80%). A statistically significant difference was found between X-ray–negative and MRI-positive SIJ lesions. Age, disease duration, and clinical as well as laboratory indices of disease activity were associated with the number of SIJ lesion patterns detected on MRI. In particular, CRP, BASDAI, and ASDAS-CRP showed a positive correlation with the number of sacroiliac joint lesion patterns observed on MRI. Age and disease duration were inversely correlated with the MRI inflammation severity index.