Đặc điểm rối loạn chức năng tuyến giáp và kết cục thai kỳ ở thai phụ nhập viện sinh tại Bệnh viện Đa khoa tỉnh Bình Dương

Abstract

Thyroid dysfunction is the second most common endocrine disorder in pregnancy and may adversely affect both mother and fetus, particularly in the third trimester in general and in the intrapartum period in particular. Therefore, we conducted a cross-sectional study in 53 pregnant women diagnosed with thyroid dysfunction to describe clinical features, thyroid hormone levels, clinical phenotypes, and pregnancy outcomes among women admitted for delivery with thyroid dysfunction. Hyperthyroidism predominated, including overt (49.1%) and subclinical disease (30.2%). Overt and subclinical hypothyroidism accounted for 5.7% and 3.8%, respectively, while 11.3% had isolated low free thyroxine (FT4). The most common symptoms of hyperthyroidism were tachycardia (71.4%) and hand tremor (59.5%). Hypothyroidism was less symptomatic, with constipation being the most frequent manifestation (63.6%). No postpartum hemorrhage or maternal or neonatal deaths were observed. However, the hyperthyroidism group tended to have higher rates of preterm birth and postpartum complications. In conclusion, pregnancy-related thyroid dysfunction was predominantly hyperthyroidism; enhanced screening combining clinical assessment and laboratory testing is needed to enable timely treatment.