Serum CA-125 levels and associated factors in patients with acute myocardial infarction
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Abstract
An analytical cross-sectional study was conducted on 130 patients with acute myocardial infarction at Tay Ninh General Hospital from June 2025 to February 2026 to investigate serum CA-125 levels and associated factors. The median CA-125 concentration was 29.95 (12.60 – 48.60) U/mL. CA-125 levels were significantly higher in patients with Killip class II–IV and in those with LVEF < 40% compared with the corresponding comparison groups, with p < 0.001. CA-125 was positively correlated with NT-proBNP (r = 0.705; p < 0.001) and high-sensitivity troponin T at 0 hour (r = 0.200; p = 0.023) and inversely correlated with LVEF (r = -0.441; p < 0.001) and eGFR (r = -0.283; p = 0.001). In the multivariable model, Killip class II–IV, LVEF < 40% and reduced eGFR remained significantly associated with CA-125 levels. These findings suggest that CA-125 may serve as an adjunctive marker for assessing congestion and hemodynamic burden, although they should be interpreted cautiously.
Article Details
Keywords
CA-125, acute myocardial infarction, associated factors
References
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