Predictive validity of the world federation of neurosurgical societies (wfns) grading scale for the poor outcome after aneurysmal subarachnoid hemorrhage

Vuong Thi Thu Hien, Luong Quoc Chinh

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Abstract

This study aimed to determine the relation between the World Federation of Neurosurgical Societies (WFNS) and Hunt and Hess (H&H) grading scales and the actual outcome and compared the prognostic accuracy of both scales. We retrieved data on all aneurysmal SAH patients admitted to three central hospitals in Hanoi, Vietnam between August 2019 and August 2020. Using logistic regression, we calculated odds ratio (OR) with a corresponding 95% confidence interval (CI) for poor outcome at 90 days for each category in comparison with the lowest category of both scales. Areas under the curve of the corresponding receiver operator characteristic curve were calculated. We included 168 patients (≥ 18 years old). For the WFNS, OR ranged from 2.15 (95% CI, 0.50 - 9.20) to 37.44 (95% CI, 9.53 - 163.25) and increased less evenly than the H&H, with OR ranging from 0.85 (95% CI, 0.23 - 3.19) to 30.11 (95% CI, 8.66 - 104.75). Areas under the curve were 0.81 (95% CI, 0.73 - 0.88) for the WFNS and 0.81 (95% CI, 0.74 - 0.89) for the H&H. Both WFNS and H&H scales have a good discriminatory ability for patient prognosis. Because the OR of the WFNS increases less gradually, it is not preferable to the H&H scale.

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References

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