Magnetic resonance imaging features and factors associated with complex anal fistulas according to the Garg classification

Tran Thi Nhat Anh, Nguyen Thi Men, Nguyen Van Tuan, Tran Thu Huyen, Nguyen Duy Hung

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Abstract

A cross-sectional descriptive study was conducted on 240 patients with anal fistula who underwent preoperative magnetic resonance imaging (MRI) at Viet Duc University Hospital from June 2024 to March 2026, aiming to describe MRI features and identify factors associated with complex anal fistulas according to the Garg classification. Anal fistulas were categorized into two groups: simple (Garg I–II) and complex (Garg III–V). MRI features including internal opening, secondary tracts, abscesses, horseshoe fistulas, and the number of external openings were analyzed using univariate and multivariate logistic regression. The mean age was 40.10 ± 13.78 years old, predominantly males at 89.2%. The prevalence of complex fistulas was 47.1%. MRI identified the internal opening in more than 96% of cases in both groups. Secondary tracts, abscesses, horseshoe fistulas, and ≥ 2 external openings were significantly more frequent in the complex fistula group (p < 0.05). Multivariate analysis demonstrated that secondary tracts (adjusted OR = 5.03; p < 0.001) and abscesses (adjusted OR = 3.16; p < 0.001) were independently associated with complex anal fistulas. MRI has high value in the classification and treatment planning of anal fistulas.

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References

1. Parks AG. Pathogenesis and Treatment of Fistula-in-Ano. Br Med J. 1961;1(5224):463-460.2. doi:10.1136/bmj.1.5224.463
2. Whiteford MH, Kilkenny J, Hyman N, et al. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum. 2005;48(7):1337-1342. doi:10.1007/s10350-005-0055-3
3. Vogel JD, Johnson EK, Morris AM, et al. Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula. Diseases of the Colon & Rectum. 2016;59(12):1117. doi:10.1097/DCR.0000000000000733
4. Sahni VA, Ahmad R, Burling D. Which method is best for imaging of perianal fistula? Abdom Imaging. 2008;33(1):26-30. doi:10.1007/s00261-007-9309-y
5. Garg P. Comparing existing classifications of fistula-in-ano in 440 operated patients: Is it time for a new classification? A Retrospective Cohort Study. International Journal of Surgery. 2017;42:34-40. doi:10.1016/j.ijsu.2017.04.019
6. Garg P. Assessing validity of existing fistula-in-ano classifications in a cohort of 848 operated and MRI-assessed anal fistula patients – Cohort study. Ann Med Surg (Lond). 2020;59:122-126. doi:10.1016/j.amsu.2020.09.022
7. Michael R Torkzad, Urban Karlbom. MRI for assessment of anal fistula. Insights Imaging. 2010 May 27;1(2):62-71. doi: 10.1007/s13244-010-0022-y
8. Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. British Journal of Surgery. 1976;63(1):1-12. doi:10.1002/bjs.1800630102
9. Yildirim N, Gökalp G, Öztürk E, et al. Ideal combination of MRI sequences for perianal fistula classification and the evaluation of additional findings for readers with varying levels of experience. Diagn Interv Radiol. 2012;18(1):11-19. doi:10.4261/1305-3825.DIR.4092-10.1
10. D V, C P, L N, H L, T N, H P. The role of magnetic resonance imaging in the preoperative evaluation of anal fistulas. Scientific reports. 2019;9(1). doi:10.1038/s41598-019-54441-2
11. Sudoł-Szopińska I, Garg P, Mellgren A, et al. Structured magnetic resonance imaging and endoanal ultrasound anal fistulas reporting template (SMART): An interdisciplinary Delphi consensus. World Journal of Gastrointestinal Surgery. 2024;16(10):3288-3300. doi:10.4240/wjgs.v16.i10.3288
12. MRI of perianal fistulas: bridging the radiological–surgical divide. Abdominal Radiology. Springer Nature Link. Accessed May 7, 2026. https://link.springer.com/article/10.1007/s00261-012-9965-4
13. Pham MD, Nguyen TT, Nguyen HT, Vo MTT, Pham NTT. Đánh giá đặc điểm rò hậu môn phức tạp trên cộng hường từ theo phân loại Garg. UD-JST. Published online September 30, 2025:104-108. doi:10.31130/ud-jst.2025.23(9A).273