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Published: 2022-03-01
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DOI: https://doi.org/10.52852/tcncyh.v151i3.628
Issue
Vol. 151 No. 3 (2022)
Section
Các bài báo
How to Cite
Vinh, N. A. ., & Hoà, P. H. . (2022). Cut-off point value of serum NT-ProBNP in diagnosis of heart failure in children. Journal of Medical Research, 151(3), 153-161. https://doi.org/10.52852/tcncyh.v151i3.628

Cut-off point value of serum NT-ProBNP in diagnosis of heart failure in children

Ngo Anh Vinh, Pham Huu Hoa

Main Article Content

Abstract

 This study aimed to determine the optimal cut-off point of serum NT-ProBNP concentrations in
the diagnosis of heart failure in children. Serum NT-ProBNP concentrations were measured in 136
children who had heart failure and 272 healthy children from Vietnam National Children’s Hospital.
The age range of all children were from 1 month to 15 years. The NT-ProBNP concentrations of
the heart failure group were significantly higher than those of the healthy group (p < 0.001). The
diagnostic cut-off concentration was 314.5 pg/ml with a sensitivity of 88.2%, specificity of 66.7%,
and an area under the ROC curve of 0.81. The cut-off point of serum NT-ProBNP concentration
of 314.5 pg/ml was can serve as a diagnostic tool for heart failure among children in this study.

Article Details

Keywords

NT-ProBNP, cut-off point, heart failure, children

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