Prevalence of eye diseases in renal patients eligible for kidney transplant

Nguyen Le Trung, Phạm Quoc Toan, Vu Anh Tuan

Main Article Content

Abstract

This study was to determine the rate of eye diseases in patients preparing for kidney transplant at Military Hospital 103 and to describe associated factors. This was a Cross-sectional description study of 89 end-stage renal failure patients with indications for kidney transplantation at Military Hospital 103 to evaluate numerous eye diseases, including dry eye, corneal calcification, cataracts, and hypertensive retinopathy. The rate of retinal damage due to hypertension is 74.16%, dry eye disease is 71.91%, corneal calcification damage is 53.93%, and cataract rate is 16.85%. Factors that correlate with these diseases include age, sex, cause of kidney failure, and length of treatment for kidney disease.

Article Details

References

1. Johansen KL, Chertow GM, Foley RN, et al. US Renal Data System 2020 Annual Data Report: Epidemiology of Kidney Disease in the United States. American Journal of Kidney Diseases. 2021-04-01 2021;77(4):A7-A8. doi:10.1053/j.ajkd.2021.01.002
2. Abecassis M, Bartlett ST, Collins AJ, et al. Kidney transplantation as primary therapy for end-stage renal disease: a National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) conference. Clin J Am Soc Nephrol. Mar 2008;3(2):471-80. doi:10.2215/cjn.05021107
3. Thomas AG, Ruck JM, Chu NM, et al. Kidney transplant outcomes in recipients with visual, hearing, physical and walking impairments: a prospective cohort study. Nephrol Dial Transplant. Jul 1 2020;35(7):1262-1270. doi:10.1093/ndt/gfz164
4. Wang T-J, Wu C-K, Hu C-C, Keller JJ, Lin H-C. Increased risk of co-morbid eye disease in patients with chronic renal failure: a population-based study. Ophthalmic epidemiology. 2012;19(3):137-143.
5. Hsiao C-H, Chao A, Chu S-Y, et al. Association of severity of conjunctival and corneal calcification with all-cause 1-year mortality in maintenance haemodialysis patients. Nephrology Dialysis Transplantation. 2010;26(3):1016-1023. doi:10.1093/ndt/gfq485
6. Lwanga SK, Lemeshow S, World Health O. Sample size determination in health studies: a practical manual / S. K. Lwanga and S. Lemeshow. Geneva: World Health Organization; 1991.
7. Porter R, Crombie AL. Corneal and conjunctival calcification in chronic renal failure. Br J Ophthalmol. May 1973;57(5):339-43. doi:10.1136/bjo.57.5.339
8. Buratto L, Apple DJ. Phacoemulsification: principles and techniques. Slack Incorporated; 2003.
9. Wong TY, Coresh J, Klein R, et al. Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study. Journal of the American society of nephrology. 2004;15(9):2469-2476.
10. Shrinkhal, Verma R, Singh A. Diagnosis of Dry Eye. Dry Eye [Working Title]. IntechOpen; 2021.
11. Bergler-Klein J. What’s new in the ESC 2018 guidelines for arterial hypertension: The ten most important messages. Wien Klin Wochenschr. 2019;131(7-8):180-185. doi:10.1007/s00508-018-1435-8
12. Cobo G, Hecking M, Port FK, et al. Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and haemodialysis. Clin Sci (Lond). Jul 1 2016;130(14):1147-63. doi:10.1042/cs20160047
13. Thio CHL, Vart P, Kieneker LM, Snieder H, Gansevoort RT, Bültmann U. Educational level and risk of chronic kidney disease: longitudinal data from the PREVEND study. Nephrology Dialysis Transplantation. 2018;35(7):1211-1218. doi:10.1093/ndt/gfy361
14. Wong CW, Wong TY, Cheng CY, Sabanayagam C. Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways. Kidney Int. Jun 2014;85(6):1290-302. doi:10.1038/ki.2013.491
15. Wang TJ, Wu CK, Hu CC, Keller JJ, Lin HC. Increased risk of co-morbid eye disease in patients with chronic renal failure: a population-based study. Ophthalmic Epidemiol. Jun 2012;19(3):137-43. doi:10.3109/09286586.2012.680531
16. Kabedi NN, Mwanza JC, Lepira FB, Kayembe TK, Kayembe DL. Hypertensive retinopathy and its association with cardiovascular, renal and cerebrovascular morbidity in Congolese patients. Cardiovasc J Afr. Sep-Oct 2014;25(5):228-32. doi:10.5830/cvja-2014-045
17. Aktaş S, Sağdık HM, Aktaş H, et al. Tear function in patients with chronic renal failure undergoing hemodialysis. Renal failure. 2015;37(2):245-248.
18. Klaassen-Broekema N, Van Bijsterveld O. Limbal and corneal calcification in patients with chronic renal failure. British journal of ophthalmology. 1993;77(9):569-571.
19. Sariyeva Ismayılov A, Aydin Guclu O, Erol HA. Ocular manifestations in hemodialysis patients and short-term changes in ophthalmologic findings. Therapeutic Apheresis and Dialysis. 2021;25(2):204-210.
20. Brown CJ, Akaichi F. Vitamin D deficiency and posterior subcapsular cataract. Clin Ophthalmol. 2015;9:1093-8. doi:10.2147/opth.S84790
21. Klein BE, Klein R, Lee KE. Renal function abnormalities and incident cataract after a five-year interval: The Beaver Dam Eye Study. Current eye research. 1998;17(7):720-725.
22. Mondal R, Matin M, Rani M, et al. Prevalence and Risk Factors of Hypertensive Retinopathy in Hypertensive Patients. Journal of Hypertension: Open Access. 01/01 2017;06doi:10.4172/2167-1095.1000241
23. Seyahi N, Altiparmak MR, Kahveci A, et al. Association of conjunctival and corneal calcification with vascular calcification in dialysis patients. Am J Kidney Dis. Mar 2005;45(3):550-6. doi:10.1053/j.ajkd.2004.11.002
24. Vehof J, Sillevis Smitt-Kamminga N, Nibourg SA, Hammond CJ. Sex differences in clinical characteristics of dry eye disease. Ocul Surf. Apr 2018;16(2):242-248. doi:10.1016/j.jtos.2018.01.001