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Published: 2022-03-10
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DOI: https://doi.org/10.52852/tcncyh.v150i2.736
Issue
Vol. 150 No. 2 (2022)
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Hà, H. T. A. . ., Hoàng, T. H. ., Trung, N. V., Thanh, N. H. ., Thái, P. D. ., & Hạnh, N. T. H. . (2022). Assessment of the antbiotic resitance of Enterococcus faecalis harbor vancomycin resistant genes in humans, animals, food and environment. Journal of Medical Research, 150(2), 88-95. https://doi.org/10.52852/tcncyh.v150i2.736 (Original work published February 22, 2022)

Assessment of the antbiotic resitance of Enterococcus faecalis harbor vancomycin resistant genes in humans, animals, food and environment

Hoang Thi An Ha, Tran Huy Hoang, Nguyen Vu Trung, Nguyen Ha Thanh, Pham Duy Thai, Ngo Thi Hong Hanh

Main Article Content

Abstract

Vancomycin-resistant enterococcus is a worldwide threat not only in hospitals, but also in communities. The occurrence of VRE may be related to the use of avopacin - a growth factor in animals. VRE can spreads to people, food, wastewater and further through intermediate vectors such as flies. 709 strains of E. faecalis had been isolated from humans, domestic animals, flies, and wastewater from livestock farms and from food in neighboring markets. By PCR, the genes related to vancomycin resistance were identified, including van A, van B, van C1, van C2, van D, van M and van N. There were 24 strains positive for van C (3.4%), of which 15 strains carry the van C1 gene, 9 strains carry the van C2 gene. All other van gene was not detected. Using MIC technique to test for vancomycin susceptibility, only 3/709 strains (accounting for 0.4%) exhibiting vancomycin-resistant phenotype with MIC = 32µg/ml (according to CLSI 2020) are derived from human feces and flies. Vancomycin resistant E. faecalis rate in the community is low, but it is still a potential threat to human health.

Article Details

Keywords

VRE (Vancomycin resistant enterococci), E. faecalis, antibiotic resistance, vancomycin

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