Tổng quan điều trị ung thư biểu mô tế bào vảy lưỡi di động
Nội dung chính của bài viết
Tóm tắt
Nghiên cứu tổng quan luận điểm về các phương pháp điều trị ung thư biểu mô tế bào vảy lưỡi di động. Với mục tiêu nhận xét phương pháp điều trị nào hiệu quả. Nghiên cứu trên các tài liệu bằng tiếng Anh công bố trên Pubmed về kết quả điều trị ung thư biểu mô vảy lưỡi, từ năm 2014 đến nay được tìm kiếm và sàng lọc theo mô hình PRISMA. Dữ liệu được trích xuất bởi tác giả theo danh sách các biến số. Có 34 bài báo đáp ứng tiêu chí để đưa vào phân tích (n = 52.396 bệnh nhân). Các chỉ số sinh tồn được đánh giá theo phương pháp Kaplan Meier. Nghiên cứu cho thấy ở giai đoạn I-II, phẫu thuật cắt rộng cách bờ tổn thương 5 - 10mm cho hiệu quả kiểm soát khối u. Giai đoạn III và IV với kích thước tổn thương lớn hơn yêu cầu phẫu thuật nửa lưỡi hoặc toàn bộ lưỡi và tạo hình khuyết hổng. Các khối u nguy cơ tái phát cao, điều trị xạ trị hoặc hóa xạ trị bổ trợ tăng hiệu quả kiểm soát khối u. Với giai đoạn IVc đã xuất hiện di căn xa, cân nhắc các điều trị triệt căn và ưu tiên điều trị giảm nhẹ.
Chi tiết bài viết
Từ khóa
Ung thư biểu mô tế bào vảy, ung thư lưỡi, phân độ TNM
Tài liệu tham khảo
1. Freddie Bray.Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA: A Cancer Journal for Clinicians. 2018;68(6):394-424.
2. Nguyễn Hồng Nhung, Lê Văn Sơn.Tình hình ung thư khoang miệng tại bệnh viện Răng Hàm Mặt TW Hà Nội giai đoạn 2015-2019. Tạp chí Y học Việt Nam. 2020;488:61-64.
3. Ana Carolina da Silva Souto, Anke Bergmann, Héliton Spíndola Antunes, et al. Epidemiology of tongue squamous cell carcinoma: A retrospective cohort study. Oral diseases. 2023;29(2):402-410.
4. Aurore Goineau. Postoperative interstitial brachytherapy for resectable squamous cell carcinoma of the tongue. Brachytherapy. 2015; 14(1):71-76.
5. Cesare Piazza. Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes. Head and Neck. 2019; 41(1):110-115.
6. Chun-Ta Liao. Clinical Outcomes in pT4 Tongue Carcinoma are Worse than in pT3 Disease: How Extrinsic Muscle Invasion Should be Considered? Annals of surgical oncology.2017;24(9):2570-2579.
7. Cristian Udovicich. Contralateral neck failure in oral tongue cancer: Outcomes from two centers using predefined treatment criteria. Head and Neck. 2021;43(7):2024-2031.
8. Doh Young Lee. Survival and recurrence of resectable tongue cancer: Resection margin cutoff value by T classification. Head and Neck. 2018;40(2):283-291.
9. H Iftikhar. Lymph node ratio as a prognostic marker of oral tongue squamous cell carcinoma: a cohort study. Annals of the Royal College of Surgeons of England. 2020;102(9): 726-732.
10. H S Ong. Does a mandibular access osteotomy improve survival in pT2 oral tongue cancers? Retrospective study at a single institution. International journal of oral and maxillofacial surgery. 2018;47(3):289-295.
11. Hoshino Terada. An examination of the cutoff value of the depth of invasion for prophylactic neck dissection in stage I/II tongue cancer. Acta otolaryngologica. 2020;140(5): 422-426.
12. Ilia Ianovski. The role of brachytherapy for margin control in oral tongue squamous cell carcinoma. Journal of otolaryngology - head and neck surgery. 2020;49(1).
13. James Daniell. Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis. Oral oncology.2020;111.
14. Jamie R Oliver. Survival of oral tongue squamous cell carcinoma in young adults. Head and Neck. 2019;41(9):2960-2968.
15. Jose L López-Cedrún. A 22 years survival and prognostic factors analysis in a homogeneous series of 64 patients with advanced cancer of the tongue and the floor of the mouth. Journal of cranio-maxillo-facial surgery. 2015;43(3):376-381.
16. Julius Moratin. The occurrence of cervical metastases in squamous cell carcinoma of the tongue: Is there a rationale for bilateral neck dissection in early-stage tumors?. Journal of cranio-maxillo-facial surgery. 2019; 47(7):1134-1138.
17. Kanako Takayama. Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III-IVB tongue cancer. Journal of cancer research and clinical oncology. 2016;142(3):659-667.
18. Kenji Mitsudo. Chemoradiotherapy using retrograde superselective intra-arterial infusion for tongue cancer: Analysis of therapeutic results in 118 cases. Oral oncology. 2018;79:71-77.
19. L Hingsammer. The influence of lymph node ratio on survival and disease recurrence in squamous cell carcinoma of the tongue. International journal of oral and maxillofacial surgery. 2019; 48(7):851-856.
20. Laith Mukdad. Oral tongue squamous cell carcinoma survival as stratified by age and sex: A surveillance, epidemiology, and end results analysis. Laryngoscope. 2019; 129(9):2076-2081.
21. Masaru Konishi.Treatment outcomes of real-time intraoral sonography-guided implantation technique of 198Au grain brachytherapy for T1 and T2 tongue cancer. Journal of radiation research. 2021;62(5):871-876.
22. Miguel Angel Santos. High-dose-rate interstitial brachytherapy boost in inoperable locally advanced tongue carcinoma. Brachytherapy. 2017;16(6):1213-1218.
23. Mitsunobu Otsuru. A Multicenter Retrospective Study of Elective Neck Dissection for T1-2N0M0 Tongue Squamous Cell Carcinoma: Analysis Using Propensity Score-Matching. Annals of surgical oncology. 2019;26(20):555-563.
24. Mitsuo Goto. Prognostic factors and outcomes for salvage surgery in patients with recurrent squamous cell carcinoma of the tongue. Asia Pacific journal of clinical oncology. 2016;12(1):141-148.
25. Qigen Fang, Peng Li, Jinxing Qi, et al. Value of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue. Laryngoscope. 2019;129(11):2527-2530.
26. R Katna, B Bhosale, A Deshpande, et al. Oncological outcomes in patients undergoing major glossectomy for advanced carcinoma of the oral tongue. Annals of the Royal College of Surgeons of England. 2020;102(7):514-518.
27. Rattawut Wiengnon. Imaging nodal volume and survival in oral tongue cancer with cervical lymph node metastasis. Brazilian journal of otorhinolaryngology. 2023;89(4).
28. Rayan Mroueh, Aaro Haapaniemi, Antti Mäkitie. Improved outcomes with oral tongue squamous cell carcinoma in Finland. Head and Neck. 2017;39(7):1306-1312.
29. Renata Miranda Rodrigues. How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma. Journal of applied oral science. 2019.
30. Samantha Tam. Depth of invasion as a predictor of nodal disease and survival in patients with oral tongue squamous cell carcinoma. Head and Neck. 2019;41(1):177-184.
31. Shih-Jung Cheng. Comparison of long-term outcomes between pull-through resection and mandibular lip-split surgery for T4a tongue/floor of mouth cancers. Head and Neck. 2018; 40(1):144-153.
32. Shinichiro Kina. Impact of metronomic neoadjuvant chemotherapy on early tongue cancer. Cancer chemotherapy and pharmacology. 2016;78(4):833-840.
33. Shuhei Minamiyama. Retrograde superselective intra-arterial chemotherapy and daily concurrent radiotherapy for T2-4N0 tongue cancer: control of occult neck metastasis. Oral surgery, oral medicine, oral pathology and oral radiology. 2017;124(1):16-23.
34. Suhas Kodasoge Rajappa. Survival benefits of adjuvant radiation in the management of early tongue cancer with depth of invasion as the indication. Head and Neck. 2018;40(10): 2263-2270.
35. Tapan D Patel. Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis. Otolaryngology-head and neck surgery. 2016;155(4):588-597.
36. Thomas Mücke. Tumor thickness and risk of lymph node metastasis in patients with squamous cell carcinoma of the tongue. Oral oncology. 2016;53:80-84.
37. Y Decroix, N A Ghossein. Experience of the Curie Institute in treatment of cancer of the mobile tongue: I. Treatment policies and result. Cancer. 1981;47(3):496-502.
38. Wang Ling. Survival pattern and prognostic factors of patients with squamous cell carcinoma of the tongue: a retrospective analysis of 210 cases. Journal of oral and maxillofacial surgery. 2013;71(4):775-85.
39. Đinh Xuân Cường, Lê Văn Quảng. Kết quả sống thêm ung thư lưỡi giai đoạn T1-2N1M0 bằng phẫu thuật kết hợp hoá xạ trị đồng thời tại Bệnh viện K . Tạp chí Nghiên cứu Y học. 2021;137(1).
2. Nguyễn Hồng Nhung, Lê Văn Sơn.Tình hình ung thư khoang miệng tại bệnh viện Răng Hàm Mặt TW Hà Nội giai đoạn 2015-2019. Tạp chí Y học Việt Nam. 2020;488:61-64.
3. Ana Carolina da Silva Souto, Anke Bergmann, Héliton Spíndola Antunes, et al. Epidemiology of tongue squamous cell carcinoma: A retrospective cohort study. Oral diseases. 2023;29(2):402-410.
4. Aurore Goineau. Postoperative interstitial brachytherapy for resectable squamous cell carcinoma of the tongue. Brachytherapy. 2015; 14(1):71-76.
5. Cesare Piazza. Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes. Head and Neck. 2019; 41(1):110-115.
6. Chun-Ta Liao. Clinical Outcomes in pT4 Tongue Carcinoma are Worse than in pT3 Disease: How Extrinsic Muscle Invasion Should be Considered? Annals of surgical oncology.2017;24(9):2570-2579.
7. Cristian Udovicich. Contralateral neck failure in oral tongue cancer: Outcomes from two centers using predefined treatment criteria. Head and Neck. 2021;43(7):2024-2031.
8. Doh Young Lee. Survival and recurrence of resectable tongue cancer: Resection margin cutoff value by T classification. Head and Neck. 2018;40(2):283-291.
9. H Iftikhar. Lymph node ratio as a prognostic marker of oral tongue squamous cell carcinoma: a cohort study. Annals of the Royal College of Surgeons of England. 2020;102(9): 726-732.
10. H S Ong. Does a mandibular access osteotomy improve survival in pT2 oral tongue cancers? Retrospective study at a single institution. International journal of oral and maxillofacial surgery. 2018;47(3):289-295.
11. Hoshino Terada. An examination of the cutoff value of the depth of invasion for prophylactic neck dissection in stage I/II tongue cancer. Acta otolaryngologica. 2020;140(5): 422-426.
12. Ilia Ianovski. The role of brachytherapy for margin control in oral tongue squamous cell carcinoma. Journal of otolaryngology - head and neck surgery. 2020;49(1).
13. James Daniell. Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis. Oral oncology.2020;111.
14. Jamie R Oliver. Survival of oral tongue squamous cell carcinoma in young adults. Head and Neck. 2019;41(9):2960-2968.
15. Jose L López-Cedrún. A 22 years survival and prognostic factors analysis in a homogeneous series of 64 patients with advanced cancer of the tongue and the floor of the mouth. Journal of cranio-maxillo-facial surgery. 2015;43(3):376-381.
16. Julius Moratin. The occurrence of cervical metastases in squamous cell carcinoma of the tongue: Is there a rationale for bilateral neck dissection in early-stage tumors?. Journal of cranio-maxillo-facial surgery. 2019; 47(7):1134-1138.
17. Kanako Takayama. Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III-IVB tongue cancer. Journal of cancer research and clinical oncology. 2016;142(3):659-667.
18. Kenji Mitsudo. Chemoradiotherapy using retrograde superselective intra-arterial infusion for tongue cancer: Analysis of therapeutic results in 118 cases. Oral oncology. 2018;79:71-77.
19. L Hingsammer. The influence of lymph node ratio on survival and disease recurrence in squamous cell carcinoma of the tongue. International journal of oral and maxillofacial surgery. 2019; 48(7):851-856.
20. Laith Mukdad. Oral tongue squamous cell carcinoma survival as stratified by age and sex: A surveillance, epidemiology, and end results analysis. Laryngoscope. 2019; 129(9):2076-2081.
21. Masaru Konishi.Treatment outcomes of real-time intraoral sonography-guided implantation technique of 198Au grain brachytherapy for T1 and T2 tongue cancer. Journal of radiation research. 2021;62(5):871-876.
22. Miguel Angel Santos. High-dose-rate interstitial brachytherapy boost in inoperable locally advanced tongue carcinoma. Brachytherapy. 2017;16(6):1213-1218.
23. Mitsunobu Otsuru. A Multicenter Retrospective Study of Elective Neck Dissection for T1-2N0M0 Tongue Squamous Cell Carcinoma: Analysis Using Propensity Score-Matching. Annals of surgical oncology. 2019;26(20):555-563.
24. Mitsuo Goto. Prognostic factors and outcomes for salvage surgery in patients with recurrent squamous cell carcinoma of the tongue. Asia Pacific journal of clinical oncology. 2016;12(1):141-148.
25. Qigen Fang, Peng Li, Jinxing Qi, et al. Value of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue. Laryngoscope. 2019;129(11):2527-2530.
26. R Katna, B Bhosale, A Deshpande, et al. Oncological outcomes in patients undergoing major glossectomy for advanced carcinoma of the oral tongue. Annals of the Royal College of Surgeons of England. 2020;102(7):514-518.
27. Rattawut Wiengnon. Imaging nodal volume and survival in oral tongue cancer with cervical lymph node metastasis. Brazilian journal of otorhinolaryngology. 2023;89(4).
28. Rayan Mroueh, Aaro Haapaniemi, Antti Mäkitie. Improved outcomes with oral tongue squamous cell carcinoma in Finland. Head and Neck. 2017;39(7):1306-1312.
29. Renata Miranda Rodrigues. How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma. Journal of applied oral science. 2019.
30. Samantha Tam. Depth of invasion as a predictor of nodal disease and survival in patients with oral tongue squamous cell carcinoma. Head and Neck. 2019;41(1):177-184.
31. Shih-Jung Cheng. Comparison of long-term outcomes between pull-through resection and mandibular lip-split surgery for T4a tongue/floor of mouth cancers. Head and Neck. 2018; 40(1):144-153.
32. Shinichiro Kina. Impact of metronomic neoadjuvant chemotherapy on early tongue cancer. Cancer chemotherapy and pharmacology. 2016;78(4):833-840.
33. Shuhei Minamiyama. Retrograde superselective intra-arterial chemotherapy and daily concurrent radiotherapy for T2-4N0 tongue cancer: control of occult neck metastasis. Oral surgery, oral medicine, oral pathology and oral radiology. 2017;124(1):16-23.
34. Suhas Kodasoge Rajappa. Survival benefits of adjuvant radiation in the management of early tongue cancer with depth of invasion as the indication. Head and Neck. 2018;40(10): 2263-2270.
35. Tapan D Patel. Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis. Otolaryngology-head and neck surgery. 2016;155(4):588-597.
36. Thomas Mücke. Tumor thickness and risk of lymph node metastasis in patients with squamous cell carcinoma of the tongue. Oral oncology. 2016;53:80-84.
37. Y Decroix, N A Ghossein. Experience of the Curie Institute in treatment of cancer of the mobile tongue: I. Treatment policies and result. Cancer. 1981;47(3):496-502.
38. Wang Ling. Survival pattern and prognostic factors of patients with squamous cell carcinoma of the tongue: a retrospective analysis of 210 cases. Journal of oral and maxillofacial surgery. 2013;71(4):775-85.
39. Đinh Xuân Cường, Lê Văn Quảng. Kết quả sống thêm ung thư lưỡi giai đoạn T1-2N1M0 bằng phẫu thuật kết hợp hoá xạ trị đồng thời tại Bệnh viện K . Tạp chí Nghiên cứu Y học. 2021;137(1).