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Published: 2026-03-09
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DOI: https://doi.org/10.52852/tcncyh.v199i2.4713
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Vol. 199 No. 2 (2026)
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Các bài báo
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Hằng, H. T. T., & Dung, T. M. (2026). Predictive role of pre-pregnancy body mass index in the development of pre-eclampsia among pregnant women. Journal of Medical Research, 199(2), 172-178. https://doi.org/10.52852/tcncyh.v199i2.4713

Predictive role of pre-pregnancy body mass index in the development of pre-eclampsia among pregnant women

Ho Thi Thu Hang, Tran My Dung

Main Article Content

Abstract

A cross-sectional descriptive study was conducted among pregnant women attending the Department of Obstetrics at Vinh Long General Hospital from March 2025 to September 2025. The objective was to determine the predictive value of pre-pregnancy body mass index for the development of preeclampsia. 78 pregnant women were included, with a mean age of 26.67 ± 6.62 years old. Overweight and obese patients before pregnancy were 17.9% and 7.7%, respectively. Fourteen patients developed pre-eclampsia, accounting for 17.9%. In multivariable analysis, overweight and obesity were independent risk factors for pre-eclampsia, with an odds ratio (OR) of 5.76 (95% CI: 1.34 - 24.71). A BMI cut-off value of 22.90 kg/m² yielded an area under the curve (AUC) of 0.748 (95% CI: 0.59 - 0.91) for predicting pre-eclampsia. These findings indicate that pre-pregnancy overweight and obesity are independent factors associated with an increased risk of pre-eclampsia, and BMI has a fairly good predictive value for the development of pre-eclampsia.

Article Details

Keywords

Prepregnancy, body mass index, predictive value, preeclampsia

References

1. Bisson C, Dautel S, Patel E, Suresh S, Dauer P, Rana S. Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum. Front Med. 2023; 10: 1144170. doi: 10.3389/fmed.2023.1144170.
2. Torres-Torres J, et al. A Narrative Review on the Pathophysiology of Preeclampsia. Int J Mol Sci. 2024; 25(14): 7569. doi: 10.3390/ijms25147569.
3. Magee LA, Nicolaides KH, von Dadelszen P. Preeclampsia. N Engl J Med. 2022 May 12; 386(19): 1817-1832. doi: 10.1056/NEJMra2109523.
4. Driul L, et al. Prepregnancy body mass index and adverse pregnancy outcomes. Arch Gynecol Obstet. 2008 Jul; 278(1): 23-6. doi: 10.1007/s00404-007-0524-0.
5. Akinyemi OA, et al. Increasing Pre-pregnancy Body Mass Index and Pregnancy Outcomes in the United States. Cureus. 2022 Sep 2; 14(9): e28695. doi: 10.7759/cureus.28695.
6. Phelps NH, et al. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. The Lancet. 2024; 403: 27-50. doi: 10.1016/S0140-6736(23)02750-2.
7. Misra A. Current formula for calculating body mass index is applicable to Asian populations. Nutr Diabetes. 2019 Jan 28; 9(1): 3. doi: 10.1038/s41387-018-0070-9.
8. Phipps E. Preeclampsia: Updates in Pathogenesis, Definitions, and Guidelines. Clin J Am Soc Nephrol. 2016; 11(6): 1102-1113. doi: 10.2215/CJN.12081115.
9. Bouter AR, Duvekot JJ. Evaluation of the clinical impact of the revised ISSHP and ACOG definitions on preeclampsia. Pregnancy Hypertens. 2020 Jan; 19(1): 206-211. doi: 10.1016/j.preghy.2019.11.011.
10. Wei YM, et al. Risk of adverse pregnancy outcomes stratified for pre-pregnancy body mass index. Matern Fetal Neo Med. 2016; 29(13): 5-9. doi: 10.3109/14767058.2015.1081167.
11. Khashan AS, Kenny LC. The effects of maternal body mass index on pregnancy outcome. Eur J Epidemiol. 2009; 24(11): 697-705. doi: 10.1007/s10654-009-9375-2.
12. Doherty DA, Magann EF, Francis J, Morrison JC, Newnham JP. Pre-pregnancy body mass index and pregnancy outcomes. Int J Gynaecol Obstet. 2006 Dec; 95(3): 242-7. doi: 10.1016/j.ijgo.2006.06.021.
13. Liang CC, Chao M. Impact of prepregnancy body mass index on pregnancy outcomes, incidence of urinary incontinence and quality of life during pregnancy - An observational cohort study. Biomed J. 2020 Dec; 43(6): 476-483. doi: 10.1016/j.bj.2019.11.001.