Early outcomes of ultrasound-guided absolute ethanol sclerotherapy for benign breast cysts combined with compression bandaging
Main Article Content
Abstract
Benign breast cysts are common in women and may cause pain and anxiety, requiring treatment when symptomatic. This uncontrolled pre–post interventional study was conducted on 30 patients with 40 breast cysts to evaluate the early outcomes and factors associated with complications of ultrasound-guided absolute ethanol sclerotherapy combined with compression bandaging. Outcomes were assessed by ultrasonography 1 week after treatment. The median cyst volume decreased from 5.85 mL before treatment to 0.00 mL after treatment, with a median volume reduction rate of 100.0% (p < 0.001). Complete cyst collapse was achieved in 67.5% of cysts. Early post-procedural complications were infrequent and included skin bruising (7.5%), intracystic hemorrhage (5.0%), and ethanol leakage from the cyst cavity (2.5%). In the exploratory analysis, cysts with complications had higher pretreatment cyst volume and higher absolute injected ethanol volume than those without complications. These preliminary findings suggest that ultrasound-guided absolute ethanol sclerotherapy combined with compression bandaging is effective in reducing the volume of benign breast cysts after 1 week, with a low complication rate. Further studies with larger sample sizes and longer follow-up period are needed to evaluate long-term effectiveness and recurrence rates.
Article Details
Keywords
benign breast cysts, ethanol sclerotherapy, ultrasound-guided intervention, compression bandaging, treatment outcomes
References
2. Stachs A, Stubert J, Reimer T, et al. Benign Breast Disease in Women. Deutsches Arzteblatt international. 2019;116(33-34):565-574. doi:10.3238/arztebl.2019.0565
3. Gabriel D, Peart O. Ultrasound-Guided Breast Procedures. Journal of Radiology Nursing. 2023;42(3):284-289. doi:10.1016/j.jradnu.2023.02.007
4. Gizienski TA, Harvey JA, Sobel AH. Breast cyst recurrence after postaspiration injection of air. The breast journal. 2002;8(1):34-7. doi:10.1046/j.1524-4741.2002.08007.x
5. Gomes C, Amaral N, Marques C, et al. Sclerosis of gross cysts of the breast: a three-year study. European journal of gynaecological oncology. 2002;23(3):191-4.
6. Álvarez-Fernández D, González JL, Ayala-Luna JC, et al. Injection of absolute alcohol into cysts cavities, after cyst aspiration, for treating and reducing the rate of recurrence of benign breast cysts. Gynecological Surgery. 2010;7(3):285-288. doi:10.1007/s10397-010-0559-2
7. Duong Huong Lan, Nguyen Thu Huong, Nguyen Cong Tien, et al. To investigate the effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in symptom breast cysts. Vietnamese Journal of Radiology and Nuclear Medicine. 2022;(39):76-80. doi:10.55046/vjrnm.39.212.2020
8. Özgen A. Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts. Diagnostic and interventional radiology (Ankara, Turkey). 2016;22(3):220-3. doi:10.5152/dir.2015.15425
9. Clark RDE, Luo X, Issa PP, et al. A clinical practice review of percutaneous ethanol injection for thyroid nodules: state of the art for benign, cystic lesions. Gland surgery. 2024;13(1):108-116. doi:10.21037/gs-22-568