27. High-risk acute pulmonary embolism: The first crossectional study reported in Vietnam
Main Article Content
Abstract
High-risk pulmonary embolism (PE) is a life-threatening disorder associated with high mortality. The purpose of this study is to elucidate the clinical characteristics, laboratory investigations, and imaging findings and report the treatment outcome of these patients. This cross-sectional study included 24 patients diagnosed with high-risk acute pulmonary embolism at Hanoi Medical University Hospital and Bach Mai Hospital. The most common clinical symptom was dyspnea (20/24 patients, 83.3%) and chest pain (10/24 patients, 41.7%). Mechanical ventilation was administered to 14 of 24 patients (58.3%), 6/24 (25%) patients had cardiac arrest. The mean Vasoactive Inotrope Score was 51 and higher in the group with cardiac arrest. On computed tomography, central pulmonary artery occlusion accounted for 73.9% (17/23 patients). On echocardiography, 22 of 24 (91.7%) had right ventricular dilatation. Thrombolysis was the most common selected treatment (15/24, 62.5%), 2/24 patients were resuscitat with ECMO (8.3%). The 30-day mortality rate of the high-risk acute pulmonary embolism in our study was 41.7%. High-risk pulmonary embolism had nonspecific symptoms, required resuscitation, and had a high mortality rate. Early detection and prompt treatment are needed to reduce mortality in this group.
Article Details
Keywords
acute pulmonary embolism, high-risk, mortality, rt-PA
References
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