16. Đặc điểm lâm sàng, cận lâm sàng và một số yếu tố tiên lượng tử vong ở bệnh nhân cao tuổi bị tắc động mạch phổi cấp

Abstract

This study aimed to describe the clinical and paraclinical features of elderly patients with acute pulmonary embolism (PE) and to identify prognostic factors associated with mortality. It was a prospective observational study with a 3-month follow-up period following diagnosis. A total of 87 patients were enrolled, with a mean age of 72.6 ± 8.96 years old; 56.3% were male. Thrombolytic therapy was administered to 6.9% of patients, while the remainder received single anticoagulation administration. The overall 3-month mortality rate was 11.5%, with PE-related deaths accounting for 3.4%. Binary logistic analysis revealed that PaO2< 80mmHg on arterial blood gas (OR = 16.583, 95%CI: 1.388 - 198.1) and hemodynamic instability at admission (OR = 288.732.5; 95%CI: 7.02 - 11871.72.97 - 356.15)) were significantly associated with mortality. Notably, 45% of patients were categorized as having intermediate-low risk at diagnosis. Hemodynamic instability and reduced PaO2 remained strong predictors of mortality during the follow-up period.