25. U lympho tế bào NK/T ngoài hạch, típ mũi phát hiện sau phẫu thuật nâng mũi: Báo cáo 1 case lâm sàng hiếm gặp

Abstract

Extranodal NK/T-cell lymphoma, nasal type (ENKL) is a rare non-Hodgkin lymphoma subtype. Common clinical manifestations include swelling, nasal obstruction, and epistaxis. Diagnosis is challenging and is often at advanced stages, requiring histological examination and immunohistochemical evidence. We report a clinical case of a 47-year-old female patient who underwent augmentation rhinoplasty with alloplastic materials 3 months prior to admission. Twenty days post nose augmentation surgery, she experienced fever, discharge from the right nostril, and swelling of the right half of her face. The patient underwent surgical removal of the alloplastic implant and inflamed tissue 3 weeks later, but her fever and swelling did not improve. Hematological studies showed evidence of anemia and acute inflammation. Nasal endoscopy revealed swelling of the right nose and many necrotic scales on the nasal mucous membrane. Biopsy and immunohistochemistry results confirmed the diagnosis of ENKL. To date, ENKL is known to be a rare disease, however, the correlation between ENKL and the alloplastic implants and inflammatory response still remains unclear. The existing evidence regarding the correlation has been documented only through clinical case reports.